ABOUT US

Our long-term goals are to better understand the molecular and biological mechanisms implicated in the pathological process that leads to Alzheimer’s disease, the most frequent age related neurological disorder. More specifically, we use molecular and cellular biology, and protein engineering to identify novel mechanisms and molecules regulating the production of the amyloid-beta peptides, the causative agents of this disease. Together, our fundamental discoveries are expected to have therapeutic implications to prevent or slow down the pathogenesis of Alzheimer’s disease.

• Congratulations to Sébastien Mosser for his Best poster award at the UniL D-Day conference!
  

• The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain
  Mosser S, Alattia JR, Dimitrov M, Matz A, Pascual J, Schneider BL, Fraering PC., Hum Mol Genet. 2014 Sep 1.